Fibroblasts peak at the injury site at approximately how many days after injury?

Fibroblasts peak at the injury site at approximately how many days after injury?

• A. 3 days
• B. 5 days
• C. 7 days
• D. 14 days

Answer: (C)

Fibroblasts peak around one week after injury. After the initial inflammatory phase, fibroblasts migrate into the wound and proliferate during the proliferative phase, laying down extracellular matrix and collagen to form granulation tissue and support wound contraction. This activity reaches its maximum roughly at seven days post-injury. By about two weeks, the process shifts more toward remodeling, so fibroblast numbers and activity are no longer at their peak. Early times like three or five days show rising but not maximal fibroblast activity, while fourteen days is closer to remodeling than peak proliferation.

Fibroblasts peak around one week after injury. After the initial inflammatory phase, fibroblasts migrate into the wound and proliferate during the proliferative phase, laying down extracellular matrix and collagen to form granulation tissue and support wound contraction. This activity reaches its maximum roughly at seven days post-injury. By about two weeks, the process shifts more toward remodeling, so fibroblast numbers and activity are no longer at their peak. Early times like three or five days show rising but not maximal fibroblast activity, while fourteen days is closer to remodeling than peak proliferation.